Research priorities in spasmodic dysphonia

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Brainstem pathology in spasmodic dysphonia.

Spasmodic dysphonia (SD) is a primary focal dystonia of unknown pathophysiology, characterized by involuntary spasms in the laryngeal muscles during speech production. We examined two rare cases of postmortem brainstem tissue from SD patients compared to four controls. In the SD patients, small clusters of inflammation were found in the reticular formation surrounding solitary tract, spinal tri...

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Tremor in speakers with spasmodic dysphonia

the objective of this work is the estimation of vocal tremor in patients with spasmodic dysphonia before and after treatment, and the comparison of their tremor characteristics with those estimated from healthy speakers. as an outcome, a new tremor attribute is introduced, the deviation of the modulation level and a novel method is proposed for classifying speakers according to the prevalence o...

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Abnormal structure-function relationship in spasmodic dysphonia.

Spasmodic dysphonia (SD) is a primary focal dystonia characterized by involuntary spasms in the laryngeal muscles during speech production. Although recent studies have found abnormal brain function and white matter organization in SD, the extent of gray matter alterations, their structure-function relationships, and correlations with symptoms remain unknown. We compared gray matter volume (GMV...

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Spasmodic Dysphonia: Evidence concerning a Neurological Cause

The term spasmodic dysphonia is a recent one, suggested by Aronson et al. (1968b), as a replacement for the term spastic dysphonia. The new term was advocated because "the term spastic is commonly used to imply disease of ... pyramidal pathways", while the neurological evidence in the Aronson research concerned the extrapyramidal system. Further, Aronson et al. observed that "the strained voice...

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Acoustic correlate of vocal effort in spasmodic dysphonia.

OBJECTIVES This study characterized the relationship between relative fundamental frequency (RFF) and listeners' perceptions of vocal effort and overall spasmodic dysphonia severity in the voices of 19 individuals with adductor spasmodic dysphonia. METHODS Twenty inexperienced listeners evaluated the vocal effort and overall severity of voices using visual analog scales. The squared correlati...

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ژورنال

عنوان ژورنال: Otolaryngology–Head and Neck Surgery

سال: 2008

ISSN: 0194-5998,1097-6817

DOI: 10.1016/j.otohns.2008.05.624